Science of Aging and Cellular Regeneration

Aging is a progressive deterioration of cellular functions over time.
However, modern science shows that this process can be reversed and reprogrammed at the cellular level.

Discover Cellular Science

Fundamental Mechanisms of Aging

Over time, accumulated DNA damage, weakened mitochondria, and telomere shortening reduce cellular energy production. Decreased activity of SIRT genes and increased cellular stress limit the cell's capacity for self-renewal.

Epigenetic Changes

Epigenetic Changes

Epigenetic changes — DNA methylation and histone modifications — alter gene expression and can accelerate the aging process.

Environmental stress and inflammation disrupt this order, reducing the cell's capacity for repair and renewal.

Telomere Shortening

Telomere Shortening

Telomeres shorten with each cell division.
When a critical length is reached, cell division stops and the aging process accelerates.

The telomerase enzyme extends cellular lifespan by slowing this shortening.

Cellular Senescence

Cellular Senescence

Aging cells stop dividing but do not die. These "zombie cells" can cause tissue damage by secreting harmful molecules into their environment.

Suppressing senescence is critical for preserving young tissues.

12 Hallmarks of Aging

Aging is a complex process that develops through the influence of multiple factors at the molecular and cellular levels. Scientists have identified 12 fundamental biological markers that lead to the decline of physiological functions. Understanding these markers enables the development of effective interventions that support healthy aging.

12 Hallmarks of Aging
12 Hallmarks of Aging
12 Hallmarks of Aging

Mitochondrial Function

Mitochondria are the powerhouses of our cells.

With age, mitochondrial function deteriorates and the production of reactive oxygen species increases. This leads to oxidative stress and accelerates cellular aging.

Interventions that support mitochondrial health show promise in slowing the aging process.

Mitochondrial Function

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